بونازوريل

Tutrasulfoneisalsocalledpatozhuli.Coccidiosisisthemostcommonandinvasivediseaseinpoultry,theharmtothebreedingindustryisconsiderable,themainmeanstocontrolthediseaseisstilldrugcontrol,patozulide(alsoknownasporazurid,totrazulsulfone,totrozulsulfoneortotriazinesulfone)isanewdrugagainstcoccidiosisdevelopedbytheGermanBayercompany.ThedrugwasapprovedbytheUSFDAin2001forthetreatmentofmammaliancentraldiseasescausedbyCoccidiasuchasNeosporahughsiandSarcocystis,comparedwiththepreviousanti-coccidiosisdrugtotrazulChemicalbookid,thebiggestfeatureofpatozulideisthatitcanpenetratetheblood-brainbarrier,directlykillprotozoalocatedinthebrainandcerebrospinalfluid,andeffectivelyrelieveEPMsymptoms.Studieshaveshownthatpatozulidekillscoccidiainanimalswithoutaffectingtheproductionofanimalautoimmunity,andwiththeenhancementofautoimmunity,diseasedanimalscangraduallygetridofdependenceondrugs,whilestudieshaveshownthatpatozulihasalowerleveloftoxiceffectsthantututratril.Therefore,Patozhulihasbettermarketdevelopmentandapplicationprospects.